Bђ "in 1951 we went to rum jungle, where ...

For years, unclear physician, a native of AustraliaBЂ ™ s hardscrabble west coast horror watched as patients with peptic ulcer disease has fallen so badly that many of them removed his stomach or blood, until they died. This doctor, therapist name Barry Marshall, suffered, because he knew that a simple treatment for ulcers that while suffering 10 percent of all adults. In 1981, Marshall began working with Robin Warren, Royal Perth Hospital pathologist, two years ago, discovered the cancer can be captured hardy, corkscrew form of bacteria called helicobacter pylori

. Biopsying patients with peptic ulcer disease and cultivation of microorganisms in the laboratory, Marshall observed not only ulcers but gastric cancer in the bowels of this infection. Treatment, he realized that it was easily available: antibbiotics. But the main gastroenterologists were scornful, holding the old idea that ulcers caused by stress. Unable to his case in studies with laboratory mice (H. pylori for

affects only primates) and prohibited experiments on humans, Marshall grew desperate. Finally, he ran an experiment on the only person sick, he can get ethically: himself. He took

H. pylori from intestinal patients, mixed it into soup, and drank it. Days passed, he developed gastritis, ulcer predecessor: he started vomiting, his breath was stink, and he felt ill and exhausted. Back in the lab, he his intestine biopsy, culturing H. pylori

and prove unequivocally that bacteria were recently sat down with Marshall DISCOVER editor Pam Weintraub in Chicago, in blue jeans and drinking water in bottles without trace

Helicobacter. Man >> << star once called BЂњthe pigs doctorBЂ "Now we can talk about their work with humor and passion of an outsider who was acquitted. For their work on H. pylori

, Marshall and Warren in common. Currently, standard treatment of ulcer treatment with antibiotics. And stomach cancerBЂ "once one of the most common forms malignancyBЂ" little remains of the Western world. Having to get rid of most of the world two diseases fear, Marshall is now turning his old enemy into an ally. As a professor of clinical microbiology at the University of Western Australia, it works on flu vaccine made by cooking weakened

Helicobacter. And in an era when many doctors dismiss unexplained conditions BЂњall in head BЂ "MarshallBЂ ™ story serves as a source of inspiration and antidote to pride in the face of uncertainty. You grew up far from big cities life. What was that? I was born in Kalgoorlie, gold mining town about 400 miles east of Perth. My father was a fitter and turner, fixing locomotives and trains. My mother was a nurse. All miners required a lot of money and a lot of drinking beer, so my mother said BЂњWeBЂ ™ I have to get out of here before we go through the rest. BЂ "In 1951 we went to Rum Jungle, where uranium was booming, but halfway we stopped in Kaniva, another Boomtown from whaling stations and high-paying job. Then my father took over the chicken factory in Perth. We never wanted for anything. It was like a TV show

Happy Days. What caused your interest in science? My mother was nursing books around. I had three brothers and we were always Electronics and dust and explosions, and welding. All I can say that some things that you get from parents through osmosis. At school I had breakfast and Cs, not so much how, but I should be done well, that medical examination of school and I had some charm in an interview, so I got into medicine. As a general practice doctor everything I wanted. I was good with patients and are wondering why it happened. Eventually I developed a more mature approach, I realized that at least 50 percent of patients were undiagnosable. You find yourself in front of unexplained illness? In medical school itBЂ ™ it is possible to get taught that you can diagnose and treat it all. But then you get to the real world and that most patients walking through your door, you have no idea whatBЂ ™ s cause of their symptoms. You can cut a person in a trillion molecules and study each and theyBЂ ™ d all perfectly normal. I was never satisfied with that, excluding these diseases, a person must be a fake illness, so I put up that many times I couldnBЂ ™ t achieve the fundamental diagnosis, and I kept an open mind. This is how you come to rethink the causes ulcers? By the 20th century, not respectable ulcer disease. Doctors say BЂњYouBЂ ™ re under great stress. BЂ "nineteenth-century Europe and America were all these crazy health resorts and quack treatments. In 1880 doctors have developed bowel surgery where they cut off the bottom of the stomach and intestines connect. WeBЂ ™ re almost sure now that the early 20th century, 100 percent of humanity has been infected

Helicobacter pylori, but you can go through their entire life and never have any symptoms. What was the worst scenario for patients with peptic ulcer disease? Ulcer with a hole in it, called the duodenum, acutely painful because of stomach acid. When you eat food, food acid washes from temporarily. When food is digested, the acid comes back and takes raw materials intestine, causing pain to start again. These problems were so common that at the Mayo Clinic was built for operation on the stomach. After this operation, half the people will feel better. But about 25 percent of these patients was cured so-called gastric cripples, anorexia and coming to full health. With so many real evidence of why the ulcer is usually classified as psychosomatic? After doctors realized that they could see the sores on X-ray machine, but of course these machines are in large cites like New York and LondonBЂ "because the doctors in these cities began detecting ulcers in urban businessmen, are likely

and was high-pressure lifestyle. Later, the scientists induced ulcers in rats by placing them in a straitjacket and dropping them into ice water. Then they discovered that can protect rats from these stress ulcers based on providing them with antacids. They made the link between ulcers, stress, and acid without proper double-blind studies, but it fits into what everybody thought. How did you come to challenge this dominant theory? I was in my third year internal medicine training, in 1981, and I had to take on the project. Robin Warren, a hospital pathologist said that he was to see these bacteria in gastric biopsy and patients with purchase strattera gastric cancer for two years, and they were all the same. What distinguishes these infections? Microorganisms in the S-shaped or spiral shape, and infections covered belly. Warren found them about 20 patients who were sent to him because the doctors thought they may have cancer. Instead of cancer, he found these bacteria. So he gave me a list and said BЂњWhy donBЂ ™ t you look at their histories and see if I theyBЂ ™ is nothing wrong with them. BЂ "It turned out that one of them, a woman in the forties, was my patient. She came in feeling nausea, chronic pain in the abdomen. We put it through the usual tests, but nothing appeared. So, of course, she was sent to a psychiatrist who put her on an antidepressant. When I saw her on the list, I thought BЂњThis pretty interesting. BЂ. "